Sperm epigenome and its potential role in transgenerational inheritance
نویسندگان
چکیده
منابع مشابه
Sperm-Mediated Transgenerational Inheritance
Spermatozoa of virtually all species can spontaneously take up exogenous DNA or RNA molecules and internalize them into nuclei. In this article I review evidence for a key role of a reverse transcriptase (RT) activity, encoded by LINE-1 retrotransposons, in the fate of the internalized nucleic acid molecules and their implication in transgenerational inheritance. LINE-1-derived RT, present in s...
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ژورنال
عنوان ژورنال: Chinese Science Bulletin
سال: 2017
ISSN: 0023-074X
DOI: 10.1360/n972016-00790